Bittium NeurOne is an innovative monitoring solution for neuroscience measurements. It is developed for the needs of medical professionals and scientists to detect simultaneously high accuracy neurophysiological signals from multiple channels without compromising data integrity. Bittium NeurOne technology challenges traditional neurophysiological laboratory systems with:
The Bittium NeurOne system is a CE approved class IIa medical device.
By incorporating the latest advances in digital signal processing the Bittium NeurOne Tesla EEG System offers more accuracy, cleaner signals, faster sampling, modular solutions and more flexibility. NeurOne uses a specially developed Tesla amplifier with built in features including high dynamic range and special reduction technology to remove magnetic artifacts for TMS-EEG and fMRI-EEG applications. The NeurOne EEG system is available in 40 to 160 channels consists of a Main Unit and 1 up to 4 Tesla 40 channel amplifiers.
Bittium NeurOne is a versatile system that can be used widely in different neuroscience and psychological applications. Bittium NeurOne™ Tesla is especially designed for use together with transcranial magnetic stimulators having extremely large dynamic range and special reduction technology to remove magnetic artifacts in short latencies. An advanced amplifier design enables using both AC and DC recording modes to be configured per the end-user's preference. The innovative Tesla MRI amplifier brings MRI compatibility to Bittium NeurOne.
The Bittium NeurOne system is designed to be used together with transcranial magnetic stimulators (TMS). High dynamic input range (+/- 430 mV in DC mode and +/-86 mV in AC mode) combined with wide analog band (DC..3500 Hz) keeps TMS induced artifacts short, allowing analysis of brain activations even in short latencies. Additionally, hardware mute function and software based online artifact reduction can be used.
EEG sample synchronized triggering: Triggers generated by the stimulation system (Presentation, Superlab, E-Prime) can be routed through the Bittium NeurOne Main Unit to the TMS device or other simulation device. Bittium NeurOne feeds out a trigger pulse in constant phase with EEG sampling allowing, accurate reproduction of TMS induced artifact for easier artifact removal.
Bittium NeurOne Tesla enables concurrent MRI and EEG measurements. When using the Bittium NeurOne Syncbox EEG acquisition is synchronized with the MRI scanner clock (e.g. 4 or 10 MHz). High dynamic input range (+/- 430 mV in DC mode and +/-86 mV in AC mode) combined with wide analog band (DC..3500 Hz) yields an accurate signal with no risk of saturation when using high gradient strengths.
The Bittium NeurOne system can handle virtually any evoked potential (EP) and event related potential (ERP) measurement task because of its extensive triggering interfaces, amount of measured channels, low noise and high sampling frequency.
EMG research with very high resolution and high amount of channels: The Bittium NeurOne system has up to 32 channels of dedicated bipolar channels for EMG use. The amount of usable channels can be increased even further by also utilizing the referential channels.
Modularity of the system enables measuring up to 4 persons simultaneously on one system with fully synchronized video camera support. When used with our Brainstorm technology (Multi Syncbox) up to 10 Bittium NeurOne hardware systems can be synchronized together allowing 30 amplifiers to run with one clock – all recorded with one computer.
Other neuroscience and psychological measurements: You name the signal, Bittium NeurOne can measure it. Additionally, Bittium can customize the Bittium NeurOne system per your application. Ask for a quote and describe your application.
EEG data can be fed into another application or analyzing computer using the Bittium NeurOne DigiOut Ethernet/UDP option. The Bittium NeurOne system quarantees a minimum delay ( <3 ms and jitter-free transfer). Additionally we have LSL proxy for DigiOut option.
Brain Computer Interface studies are made easy with a BCI2000 driver and Matlab SIMULINK driver.
For real time applications like Closed-loop TMS there is a 16 channels analog out option which allows a very low latency of 2.5 ms. The Optional Real-time Digital Out is also an option.
The video package consists of a camera with HDMI output (+ Mic In for synchronization), USB3 capture box, MPEG-2 codec and a VideoSync unit that sends triggers to the NeurOne EEG stream every 10 seconds. The same trigger is fed to the audio track of the video to allow accurate synchronization throughout the recording.
The data format of Bittium NeurOne is compatible with most popular EEG analysis modalities, including Matlab, EEGLAB, BrainVision Analyzer and BESA.
Triggers generated by the stimulation system (Presentation, Superlab, E-Prime, Matlab real-time system etc.) can be routed through the NeurOne Main Unit to any TMS device (or other devices utilizing a constant wave form). The NeurOne then feeds out a trigger pulse in constant phase to the EEG sampling rate allowing accurate reproduction of the TMS induced artifact for easier artifact removal. Please see Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact by Tomasevic et al. 2017
Data delivery is handled by the NeurOne EEG System hardware which allows the data to come out with a small ( < 3 ms) and constant delay important for Brain State or Frequency Dependent TMS applications also Closed-loop TMS. The NeurOne software with the optional Digiout function simultaneously records EEG and feeds the signals as UDP packets from the NeurOne Main Unit Ethernet/Digiout port to real-time systems including Speedgoat and Labview. Please see Real-time EEG-defined excitability states determine efficacy of TMS-induced plasticity in human motor cortex by Zrenner et al. 2018
EEG can be recorded in fMRI studies with the NeurOne Syncbox MRI to synchronize the clock for EEG acquisition to the clock output of the MRI system typically at 10 MHz. Offline analysis can be completed with BESA 7.0 (released in 2018) with 3 methods for artifact correction as published by Allen et al. 2000, Allen et al. 2000 and Moosmann et al. 2009 for fMRI-EEG studies.
The amplifier design guarantees the best possible signal quality. Tesla amplifiers have a DSP (Digital Signal Processor) that takes care of digital filtering and decimation of signals from original data sampled at 80 kHz (and high resolution of 24 bits) to the actual sampling frequency. Data is collected at a high analog bandwidth and high frequency and then the final EEG signal is produced with digital processing (using multistage FIR filtering).
Each amplifier has 32 monopolar referential channels and 8 bipolar channels. Each channel can (individually) be set to operate in AC or DC mode.
| AC Mode | DC Mode | |
|---|---|---|
| Amplifier Gain | 50 | 10 |
| Input Range | +/- 86 mV | +/- 430 mV |
| Analog Bandwidth | 0.16 Hz-3500 Hz | 0 Hz-3500 Hz |
| Noise 0-200Hz | < 0.6 uV RMS | < 0.8 uV RMS |
| Noise Full-band | < 1.5 uV RMS | < 2.0 uV RMS |
| Sensitivity | 10.2 nV/bit | 51 nV/bit |
| Impedance measurement | 1 kΩ to 50 kΩ | 1 kΩ to 50 kΩ |
The amplifier is powered with a battery pack. The battery pack allows total electrical isolation of the amplifier from physical environment. Since communication from amplifier to the Main Unit is via optical cable, there is excellent signal quality regardless of the quality of the electricity or grounding of the building. Using the battery also keeps mains frequency (50/60 Hz) out of a shielded room if used.
The main unit acts as a central hub communicating with the amplifiers and the acquisition computer. It is also an isolated connection point for triggers coming from the stimulation/cognitive testing PC. Ethernet connection (TCP/IP) to the acquisition PC gives flexibility since the computer can be located far away from test person if necessary.
| Description | Powerful and Versatile Electroencephalography Research system | |
| Monopolar Channels | 32 channels per amplifier (full system 128) – expandable to 960 with Brainstorm technology | |
| Bipolar Channels | 8 channels per amplifier (full system 32) – expandable to 240 with Brainstorm technology | |
| High level Channels | Max. 8 per amplifier, connected through isolated analog adapter (to bipolar channels), range ± 5V or ± 10V (settable) | |
| Digital (TTL) Inputs | 2 isolated trigger in/out lines, 8-bit unisolated trigger in (with Syncbox up to 10x) | |
| Sampling method | All channels sampled simultaneously | |
| Available sampling rates | NeurOne™ | NeurOne™ NeurOne™ Brainstorm technology with Syncbox |
| 250 Hz, 500 Hz, 1000 Hz, 2000 Hz, 5000 Hz, 10 kHz (160 ch) | 80 kHz (max. 10 x 20 channels, one amp/main unit), 40 kHz (max. 10 x 40 channels – one amp/main unit, 20 kHz (max. 1200 channels) | |
| 20 kHz (up to 80 ch), 40 kHz, (up to 40 ch), 80 kHz (up to 20 ch) | 250 Hz, 500 Hz, 1000 Hz, 2000 Hz, 5000 Hz, 10 kHz | |
| A/D Resolution | 24 bit | |
| Input Impedance | > 1 GΩ | |
| CMRR | Typically 106 dB | |
| DC Mode | AC Mode | |
| Bandwidth | LP: 3.5 kHz | HP: 0,16 Hz, LP: 3.5 kHz |
| Full scale Input Range | ± 430 mV | ± 86 mV |
| System Gain | 10 | 50 |
| Sensitivity | Typically | x |
| Noise |
<0.8 µV RMS (0–200 Hz) <2.0 µV RMS (DC-3500 Hz) |
<0.6 µV RMS (0.16–200 Hz) < 1.5 µV RMS (0.16–3500 Hz) |
| Transient Artifact Protection | High Speed Switch (settable) | |
| Mute | Mute for AC/DC stage (settable) | |
| Impedance measurement | 1 kΩ to 200 kΩ | |
| Connections | ||
| Tesla amplifier | Power 6V, Fibers, Cap connection (40 ch),
Bipolar/Module (8 ch incl. power for modules ± 5V max. 1000 mA) |
|
| Main unit - Black | Power 12V, Ethernet, Fibers to Headbox (x 4),
Trig In/Out (x 2), 8-bit Trig, Audio Out (2 ch) * |
|
| Main unit - High | Power 12V, Ethernet, SPI, Isolated Headbox Power (x 4), Fibers to Headbox (x 4),
Serial Port (x 3), Trig In/Out (x 2), 8-bit Trig, Analog Out (16 ch), Audio Out (2 ch) * |
|
| Syncbox | Master Trig In and Trig button, External Clock In input (BNC or fiber),
10 fiber connectors (1 Master, 9 Slave) |
|
| * optional real-time Ethernet/UDP digital out | ||
| Amplifier size/color | 16 x 12 x 8 cm, 1.260 kg, Beige (Tesla), Black (Tesla MRI) | |
| Main unit size, black | 33 x 27 x 7 cm, 2.9 kg | |
| Main unit size, high | 33 x 27 x 12 cm, 3.6 kg | |
| NeurOne™ software | 64-bit Windows, optional BCI2000 and SIMULINK driver, video.
Readers for BESA and Matlab as well as EEGLAB plug-in available for free |
|
| System Classification | MDD class lla. Type BF applied part | |
| Safety Specification | EN 60601-1, EN 60601-1-1, EN 60601-1-2, EN 60601-1-4, EN 60601-2-26 | |
| Warranty | 2 years | |
EasyCap Active:
Active electrode technology has been integrated into the new EasyCap active. Impedance conversion circuits integrated into the electrode housing allow high quality recordings even with high electrode impedance values. Thus, preparation time is reduced significantly. Additionally, environmental noise and movement artefacts are nearly eliminated. EasyCap active may be used with almost every available EEG amplifier. Connectors are available upon request.
The name EasyCap represents a specialized, unique and patented concept, consisting of the following components:
NeurOne data is compatible with many analysis tools:
Bittium NeurOne system is a multifunctional tool for both neuroscience and psychological applications. Bittium NeurOne can also be customized by combining it with other devices/modules.
Here are the examples of additional accessories:
Directive 93/42/EEC
ISO 13485:2016
Endemann, R., Kamp, SM.
Examining the role of stimulus complexity in item and associative memory.
Arian Beckmann, Tilman Stephani, Felix Klotzsche, Yonghao Chen, Simon M. Hofmann, Arno Villringer, Michael Gaebler, Vadim Nikulin, Sebastian Bosse, Peter Eisert, Anna Hilsmann.
EEG-Features for Generalized Deepfake Detection.
Pushkar Deshpande, Lindsey Van Yper, Stine Christiansen, Chrisitian Brandt, Stefan Debener, Tobias Neher.
Speech Comprehension by Cochlear Implant Users Assessed with Evoked Potentials and Response Times.
Siri-Maria Kamp, Ricarda Endemann, Luisa Knopf, Nicola K. Ferdinand.
Subjective cognitive decline in healthy older adults is associated with altered processing of negative versus positive feedback in a probabilistic learning task.
Dmitri Filimonov, Sampo Tanskanen, Antti Revonsuo, Mika Koivisto.
Is auditory awareness graded or dichotomous: Electrophysiological correlates of consciousness at different depths of stimulus processing.
Tharan Suresh, Fumiaki Iwane, Minsu Zhang, Margaret McElmurry, Muskan Manesiya, Michael V Freedberg, Sara J Hussain.
Motor sequence learning-induced corticospinal plasticity is biased towards sensorimotor mu rhythm peak phases.
Umair Hassan, Prince Okyere, Milad Amini Masouleh, Christoph Zrenner, Ulf Ziemann, Til Ole Bergmann.
Pulsed inhibition of corticospinal excitability by the thalamocortical sleep spindle.
Leon O.H. Kroczek, Andreas Mühlberger.
Neural mechanisms underlying the interactive exchange of facial emotional expressions.
Kuri Takahashi, Benedikt Glinski, Mohammed Ali Salehinejad, Asif Jamil, Acer Yu-Chan Chang, MinFang Kuo, Michael A. Nitsche.
Induction and stabilization of delta frequency brain oscillations by phase-synchronized rTMS and tACS.
Sameer A. Ashaie, Julio C. Hernandez-Pavon, Evan Houldin, Leora R. Cherney.
Behavioral, Functional Imaging, and Neurophysiological Outcomes of Transcranial Direct Current Stimulation and Speech-Language Therapy in an Individual with Aphasia.
Mohammad Ali Salehinejad.
The Impact Of Circadian Factors On Cortical Excitability, Neuroplasticity, And Cognition.
Renan H. Matsuda, Victor H. Souza, Thais C. Marchetti, Ana M. Soto, Olli-Pekka Kahilakoski, Andrey Zhdanov, Victor H.E. Malheiro, Mikael Laine, Mikko Nyrhinen, Heikki Sinisalo, Dubravko Kicic, Pantelis Lioumis, Risto J. Ilmoniemi, Oswaldo Baffa.
Robotic–electronic platform for autonomous and accurate transcranial magnetic stimulation targeting.
Lisa Haxel, Paolo Belardinelli, Maria Ermolova, Dania Humaidan, Jakob H. Macke, Ulf Ziemann.
Decoding Motor Excitability in TMS using EEG-Features: An Exploratory Machine Learning Approach.
Johanna Metsomaa, Yufei Song, Tuomas P. Mutanen, Pedro C. Gordon, Ulf Ziemann, Christoph Zrenner, Julio C. Hernandez‑Pavon.
Adapted Beamforming: A Robust and Flexible Approach for Removing Various Types of Artifacts from TMS–EEG Data.
Qi Liu, Shuyong Jia, Na Tu, Tianyi Zhao, Qiuyue Lyu, Yuhan Liu, Xiaojing Song, Shuyou Wang, Weibo Zhang, Feng Xiong, Hecheng Zhang, Yi Guo, Guangjun Wang.
Open access EEG dataset of repeated measurements from a single subject for microstate analysis.
Ho Jin Choi, Satyajeet Das, Shaoting Peng, Ruzena Bajcsy, Nadia Figueroa.
On the Feasibility of EEG-based Motor Intention Detection for Real-Time Robot Assistive Control.
Soner Ülkü, Stephan Getzmann, Edmund Wascher, Daniel Schneider.
Be prepared for interruptions: EEG correlates of anticipation when dealing with task interruptions and the role of aging.
Wala Mahmoud, David Baur, Brigitte Zrenner, Arianna Brancaccio, Paolo Belardinelli, Ander RamosMurguialday, Christoph Zrenner, Ulf Ziemann.
Brain State-dependent Repetitive Transcranial Magnetic Stimulation for Motor Stroke Rehabilitation: A Proof of Concept Randomized Controlled Trial.
Anja Meunier, Michal Robert Zák, Lucas Munz, Sofiya Garkot, Manuel Eder, Jiachen Xu, Moritz Grosse-Wentrup.
A Conversational Brain-Artificial Intelligence Interface.
Ceren Arslan, Daniel Schneider, Stephan Getzmann, Edmund Wascher, Laura-Isabelle Klatt.
The Interplay Between Multisensory Processing and Attention in Working Memory: Behavioral and Neural Indices of Audio-Visual Object Storage.
Laura-Isabelle Klatt, Christine Hucke.
Behavior and alpha-band oscillations reveal cross-modal interactions between chemosensory and auditory processing.
David Emanuel Vetter, Christoph Zrenner, Paolo Belardinelli, Tuomas Petteri Mutanen, Gábor Kozák, Laura Marzetti, Ulf Ziemann
Targeting motor cortex high-excitability states defined by functional connectivity with real-time EEG–TMS
Sixuan He, Yaru Li, Xinning Le, Xiaoyu Han, Jingfeng Lin, Xiaohang Peng, Min Li, Ruobing Yang, Dezhong Yao, Pedro A. Valdes-Sosa, and Peng Ren
Assessment of Multivariate Information Transmission in Space-Time-Frequency Domain: A Case Study for EEG Signals
Pedro C. Gordon, Yu Fei Song, D. Blair Jovellar, Maryam Rostami, Paolo Belardinelli and Ulf Ziemann
Untangling TMS-EEG responses caused by TMS versus sensory input using optimized sham control and GABAergic challenge
Giorgio Leodori, Marco Mancuso, Davide Maccarrone, Matteo Tartaglia, Antonio Ianniello, FrancescoCerto, Viola Baione, Gina Ferrazzano, Leonardo Malimpensa, Daniele Belvisi, Carlo Pozzilli, Alfredo Berardelli, Antonella Conte
Neural bases of motor fatigue in multiple sclerosis: A multimodal approach using neuromuscular assessment and TMSEEG
Xueqiao Li, Elisa Vuoriainen, Qianru Xu, Piia Astikainen.
The effect of sad mood on early sensory event-related potentials to task-irrelevant faces
Nicoletta Manzo , Giorgio Leodori , Giulia Ruocco, Daniele Belvisi , Shabbir Hussain I. Merchant , Giovanni Fabbrini , Alfredo Berardelli , Antonella Conte.
Cortical mechanisms of sensory trick in cervical dystonia
Najla Azaiez, Otto Loberg, Jarmo A. Hämäläinen , Paavo H.T. Leppänen.
Auditory P3a response to native and foreign speech in children with or without attentional deficit
Chaoxiong Ye Qianru Xu; Xueqiao Li; Elisa Vuoriainen; Qiang Liu; Piia Astikainen Institute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, China.
Alterations in working memory maintenance of fearful face distractors in depressed participants: An ERP study
Najla Azaiez, Otto Loberg, Kaisa Lohvansuu, Sari Ylinen, Jarmo A. Hämäläinen and Paavo H. T. Leppänen.
Discriminatory Brain Processes of Native and Foreign Language in Children with and without Reading Difficulties
Pushkar Deshpande, Christian Brandt, Stefan Debener and Tobias Neher.
Comparing Clinically Applicable Behavioral and Electrophysiological Measures of Speech Detection, Discrimination, and Comprehension
David Baur , Maria Ermolova , Victor Hugo Souza , Christoph Zrenner , Ulf Ziemann.
Phase-amplitude coupling in high-gamma frequency range induces LTP-like plasticity in human motor cortex: EEG-TMS evidence
Christoph Zrenner, Gábor Kozák, Natalie Schaworonkow, Johanna Metsomaa, David Baur, David Vetter, Daniel M. Blumberger, Ulf Ziemann, Paolo Belardinelli.
Corticospinal excitability is highest at the early rising phase of sensorimotor µ-rhythm
Marlene Topka, Marlieke Schneider, Christoph Zrenner, Paolo Belardinelli, Ulf Ziemann and Daniel Weiss.
Motor cortex excitability is reduced during freezing of upper limb movement in Parkinson’s disease
Julio C. Hernandez-Pavon, PhD, DSc; Nils Schneider-Garces, MS; John Patrick Begnoche, MS; Lee E. Miller, PhD; Tommi Raij, MD, PhD.
Targeted Modulation of Human Brain Interregional Effective Connectivity With Spike-timing Dependent Plasticity
Lukas Gassmann, Pedro Caldana Gordon, Ulf Ziemann Department of Neurology & Stroke, University of Tübingen, Germany.
Assessing effective connectivity of the cerebellum with cerebral cortex using TMS-EEG
Steven Pillen, Nicole Knodel, Dominik Hermle, Moritz Hanke, Ulf Ziemann, Til Ole Bergmann.
No robust online effects of transcranial direct current stimulation on corticospinal excitability
Faramosh Rashid Izullah, Mika Koivisto, Valtteri Nieminen, Mika Luimula, Heikki Hämäläinen.
Aging and sleep deprivation affect different neurocognitive stages of spatial information processing during a virtual driving task – An ERP study
Christoph Zrenner, Paolo Belardinelli, Maria Ermolova, Pedro Caldana Gordon, Matti Stenroos, Brigitte Zrenner, Ulf Ziemann.
µ-rhythm phase from somatosensory but not motor cortex correlates with corticospinal excitability in EEG-triggered TMS
Marlene Rösner, Melinda Sabo, Laura-Isabelle Klatt, Edmund Wascher & Daniel Schneider Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.
Preparing for the unknown: How working memory provides a link between perception and anticipated action
Melinda Sabo & Daniel Schneider.
Pattern reinstatement and attentional control overlap during episodic long‑term memory retrieval
Dominical Šulcová, Adriana Salatino, Adrian Ivanoiu, André Mouraux Université Catholique de Louvain.
Investigating the origin of TMS-evoked brain potentials using topographic analysis
Milad Amin Masouleh.
Optimization of Transcranial Magnetic Stimulation (TMS) parameters using concurrent TMS-EEG and TMS-fMRI
Julio C. Hernandez-Pavon, Dimitris Kugiumtzis, Christoph Zrenner, Vasilios K. Kimiskidis, Johanna Metsomaa.
Removing artifacts from TMS-evoked EEG: A methods review and a unifying theoretical framework
Tomi Waselius, Weiyong Xu, Julia I. Sparre, Markku Penttonen, and Miriam S. Nokia.
Cardiac cycle and respiration phase affect responses to the conditioned stimulus in young adults trained in trace eyeblink conditioning
Miriam Alison El Hilany-Thies.
Influence of sensorimotor µ rhythm phase and power on motor cortex excitability and plasticity induction, assessed with EEG-triggered TMS
Andrea Fabbrini, Andrea Guerra, Margherita Giangrosso, Nicoletta Manzo, Giorgio Leodori, Patrizio Pasqualetti, Antonella Conte, Vincenzo Di Lazzaro, Alfredo Berardelli.
Transcranial alternating current stimulation modulates cortical processing of somatosensory information in a frequency- and time-specific manner
Pedro Caldana Gordon, Paolo Belardinelli, MattiStenroos, Ulf Ziemann, Christoph Zrenner Department of Neurology & Stroke, University of Tübingen, Germany.
Prefrontal theta phase-dependent rTMS-induced plasticity of cortical and behavioral responses in human cortex
Siri-Maria Kamp, Glen Forester Mariana Henken Malena Vittinghoff Luisa Knopf University of Trier.
On the role of item encoding mechanisms in associative memory in young and older adults: A mass univariate ERP study
Petro Julkunen, Vasilios K Kimiskidis, Paolo Belardinelli .
Bridging the gap: TMS-EEG from Lab to Clinic
Pedro Caldana Gordon, Sara Dörre, Paolo Belardinelli, Matti Stenroos, Brigitte Zrenner, Ulf Ziemann and Christoph Zrenner.
Prefrontal Theta-Phase Synchronized Brain Stimulation With Real-Time EEG-Triggered TMS
Takayuki Onojima and Keiichi Kitajo.
A closed-loop stimulation approach with real-time estimation of the instantaneous phase of neural oscillations by a Kalman filter
Mohammad Ali Salehinejad, Elham Ghanavati, Joerg Reinders, Jan G. Hengstler, Min-Fang Kuo, Michael A. Nitsche.
Sleep-dependent upscaled excitability and saturated neuroplasticity in the human brain: From brain physiology to cognition
Casarotto S, Fecchio M, Rosanova M, Varone G, D’Ambrosio S, Sarasso S, Pigorini A, Russo S, Comanducci A, Ilmoniemi RJ, Massimini M.
The rt-TEP tool: real-time visualization of TMS-Evoked Potential to maximize cortical activation and minimize artifacts
Sara J Hussain, Mary K Vollmer, Iñaki Iturrate, Romain Quentin.
Voluntary motor commands are preferentially released during restricted sensorimotor beta rhythm phases
David Haslacher, Khaled Nasr, Stephen E. Robinson, Christoph Braun, Surjo R. Soekadar.
A set of electroencephalographic (EEG) data recorded during amplitude-modulated transcranial alternating current stimulation (AM-tACS) targeting 10-Hz steady-state visually evoked potentials (SSVEP)
Xueqiao Li, Yongjie Zhu, Elisa Vuoriainen, Chaoxiong Ye & Piia Astikainen.
Decreased intersubject synchrony in dynamic valence ratings of sad movie contents in dysphoric individuals
Giorgio Leodori, Andrea Fabbrini, Maria Ilenia De Bartolo, Matteo Costanzo, Francesco Asci, Veronica Palma, Daniele Belvisi, Antonella Conte, Alfredo Berardelli.
Cortical mechanisms underlying variability in intermittent theta-burst stimulation-induced plasticity: A TMS-EEG study
Eric J. McDermott, Johanna Metsomaa, Paolo Belardinelli, Moritz Grosse‑Wentrup, Ulf Ziemann, Christoph Zrenner.
Predicting motor behavior: an efficient EEG signal processing pipeline to detect brain states with potential therapeutic relevance for VR‑based neurorehabilitation
Takayuki Onojima and Keiichi Kitajo.
A state-informed stimulation approach with realtime estimation of the instantaneous phase of neural oscillations by a Kalman filter
Bianca Zickerick, Marlene Rösner, Melinda Sabo, Daniel Schneider.
How to refocus attention on working memory representations following interruptions—Evidence from frontal theta and posterior alpha oscillations
Esra Al, Tilman Stephani, Melina Engelhardt, Arno Villringer, Vadim Nikulin Max Planck Institute for Human Cognitive and Brain Sciences.
Cardiac Activity Impacts Cortical Motor Excitability
Sara J. Hussain , Mary K. Vollmer , Jessica Stimely , Gina Norato , Christoph Zrenner , Ulf Ziemann , Ethan R. Buch , Leonardo G. Cohen.
Phase-dependent offline enhancement of human motor memory
J.Metsomaa, P.Belardinelli, M.Ermolova, U.Ziemann, C.Zrenner
Causal decoding of individual cortical excitability states
Elina S. Kangas, Elisa Vuoriainen, Xueqiao Li, Pessi Lyyra, and Piia Astikainen.
Somatosensory Deviance Detection ERPs and Their Relationship to Analogous Auditory ERPs and Interoceptive Accuracy
Mohammad Ali Salehinejad , Miles Wischnewski, Elham Ghanavati, Mohsen Mosayebi-Samani, Min-Fang Kuo & Michael A. Nitsche.
Cognitive functions and underlying parameters of human brain physiology are associated with chronotype
Maria Ermolova, Johanna Metsomaa Christoph Zrenner, Gábor Kozák, Laura Marzetti, Ulf Ziemann.
Spontaneous phase-coupling within cortico-cortical networks: How time counts for brain-state-dependent stimulation
Opposing signatures of neural excitability and sensory input in initial cortical responses differentially predict intensity perception.
Opposing signatures of neural excitability and sensory input in initial cortical responses differentially predict intensity perception
Siri-Maria Kamp.
Preceding stimulus sequence effects on the oddball-P300 in young and healthy older adults
Maria-Ioanna Stefanou, Dragana Galevska, Christoph Zrenner, Ulf Ziemann, Jaakko O. Nieminen.
Interhemispheric symmetry of μ-rhythm phase-dependency of corticospinal excitability
David Baur , Dragana Galevska , Sara Hussain , Leonardo G. Cohen , Ulf Ziemann , Christoph Zrenner .
Induction of LTD-like corticospinal plasticity by low-frequency rTMS depends on pre-stimulus phase of sensorimotor m- rhythm
Bianca Zickerick, S. OliverKobald, Sven Thönes, Kristina Küper, Edmund Wascher, Daniel Schneider.
Don't stop me now: Hampered retrieval of action plans following interruptions
Anke Ninija Karabanov, Kristoffer Hougaard Madsen, Lærke Gebser Krohne, Hartwig Roman Siebner.
Does pericentral mu-rhythm “power” corticomotor excitability? – a matter of EEG perspective
Sven Thönes , Stefan Arnau , Edmund Wascher, Daniel Schneider.
Boosting working memory with accelerated clocks
Pekcan Ungan, Suha Yagcioglu, Ece Ayik.
Effects of aging on event-related potentials to single-cycle binaural beats and diotic amplitude modulation of a tone
Bianca Zickerick, Marlene Rösner, Melinda Sabo, and Daniel Schneider.
Frontal theta and posterior alpha oscillations reflect the reactivation of working memory representations following interruptions
Henry Railo, Ilkka Suuronen, Valtteri Kaasinen, Mika Murtojärvi, Tapio Pahikkala, and Antti Airola.
Resting state EEG as a biomarker of Parkinson’s disease: Influence of measurement conditions
Henry Railo Niklas Nokelainen, Saara Savolainen, and Valtteri Kaasinen.
Deficits in monitoring self-produced speech in Parkinson’s disease
Aqsa Shakeel, Takayuki Onojima, Toshihisa Tanaka and Keiichi Kitajo.
Real-Time Implementation of EEG Oscillatory Phase-Informed Visual Stimulation Using a Least Mean Square-Based AR Model
Nicoletta Manzo, Andrea Guerra, Margherita Giangrosso, Daniele Belvisi, Giorgio Leodori, Alfredo Berardelli* & Antonella Conte.
Investigating the effects of transcranial alternating current stimulation on primary somatosensory cortex
Maria-Ioanna Stefanou, Debora Desideri, XPaolo Belardinelli, Christoph Zrenner, and Ulf Ziemann.
Phase Synchronicity of µ-Rhythm Determines Efficacy of Interhemispheric Communication Between Human Motor Cortices
Simone Grassini, Katja Valli, Jérémie Souchet, Fabien Aubret, Giulia V.Segurini, Antti Revonsuo, Mika Koivisto.
Pattern matters: Snakes exhibiting triangular and diamond-shaped skin patterns modulate electrophysiological activity in human visual cortex
Roosa E.Kallionpää, Henri Pesonen, Annalotta Scheinin, Nils Sandman, RuutLaitio, Harry Scheinin, Antti Revonsuo, Katja Valli.
Single-subject analysis of N400 event-related potential component with five different methods
Tuominen, J., Kallio, S., Kaasinen, V.. & Railo, H. Department of Psychology, University of Turku, Finland.
Segregated brain state during hypnosis
Stephan Hertweck, Desiée Weber, Hisham Alwanni, Fabian Unruh ,Martin Fischbach, Marc Erich Latoschik , Tonio Ball.
Brain Activity in Virtual Reality: Assessing Signal Quality of High-Resolution EEG While Using Head-Mounted Displays
Sara J Hussain, Mary K Vollmer, Romain Quentin, Iñaki Iturrate, Leonardo G. Cohen.
Voluntary movement initiation is not coupled to optimal sensorimotor oscillatory phases
Debora Desideri, Christoph Zrenner, Ulf Ziemann, Paolo Belardinelli.
Phase of sensorimotor μ‐oscillation modulates cortical responses to transcranial magnetic stimulation of the human
motor cortex
Til Ole Bergmann, Anne Lieb, Christoph Zrenner ,Ulf Ziemann.
Pulsed Facilitation of Corticospinal Excitability by the Sensorimotor µ-Alpha Rhythm
Kyösti Pennanen, Johanna Närväinen, Saara Vanhatalo, Roope Raisamo, Nesli Sozer.
Effect of virtual eating environment on consumers’ evaluations of healthy and unhealthy snacks
Marlene Rösner, Stefan Arnau, Isabel Skiba , Edmund Wascher, Daniel Schneider.
The spatial orienting of the focus of attention in working memory makes use of inhibition: Evidence by hemispheric asymmetries in posterior alpha oscillations
Monika Undorf, Chimezie Obioma Amaefule, Siri-Maria Kamp.
The neurocognitive basis of metamemory: Using the N400 to study the contribution of fluency to judgments of learning
Bianca Zickerick, Sven Thönes, S. Oliver Kobald, Edmund Wascher, Daniel Schneider and Kristina Küper.
Differential Effects of Interruptions and Distractions on Working Memory Processes in an ERP Study
Christoph Zrenner, Dragana Galevska, Jaakko O. Nieminen, David Baur, Maria-Ioanna Stefanou, Ulf Ziemann.
The shaky ground truth of real-time phase estimation
David Haslacher, Khaled Nasr, Stephen E. Robinson, Christoph Braun, and Surjo R. Soekadar.
Stimulation Artifact Source Separation (SASS) for assessing electric brain oscillations during transcranial alternating current stimulation (tACS)
Leodori G, Belvisi D, De Bartolo MI, Fabbrini A, Costanzo M, Vial F, Conte A, Hallett M, Berardelli A.
Re-emergent Tremor in Parkinson's Disease: The Role of the Motor Cortex.
Stephani, , Waterstraat, G., Haufe, S., Curio, G. , Villringer, A. , Nikulin, V. V..
Temporal signatures of criticality in human cortical excitability as probed by early somatosensory responses
Stefanou, M. I., Baur, D., Belardinelli, P., Bergmann, T. O., Blum, C., Gordon, P. C., Nieminen, J. O., Zrenner, B., Ziemann, U., Zrenner, C..
Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
Pedro Caldana Gordon , Christoph Zrenner , Debora Desideri , Paolo Belardinelli , Brigitte Zrenner , André Russowsky Brunoni , Ulf Ziemann.
Modulation of cortical responses by transcranial direct current stimulation of dorsolateral prefrontal cortex: A resting- state EEG and TMS-EEG study
Brigitte Zrenner, Christoph Zrenner, Pedro Caldana Gordon, Paolo Belardinelli, Eric J. McDermott, Surjo R. Soekadar, Andreas J. Fallgatter, Ulf Ziemann, Florian Müller-Dahlhaus.
Brain oscillation-synchronized stimulation of the left dorsolateral prefrontal cortex in depression using real-time EEG- triggered TMS
Yongjie Zhu, Xueqiao Li, Tapani Ristaniemi, Fengyu Cong.
MEASURING THE TASK INDUCED OSCILLATORY BRAIN ACTIVITY USING TENSOR DECOMPOSITION
Debora Desideri, Christoph Zrenner, Pedro Caldana Gordon, Ulf Ziemann, Paolo Belardinelli.
Nil effects of μ-rhythm phase-dependent burst-rTMS on cortical excitability in humans: A resting-state EEG and TMS-EEG study
Felix A. Heilmeyer and Tonio Ball.
neurone_loader: A Python module for loading EEG data recorded with Bittium NeurOne
Giorgio Leodori, Nivethida Thirugnanasambandam, Hannah Conn, Traian Popa, Alfredo Berardelli and Mark Hallett.
Intracortical Inhibition and Surround Inhibition in the Motor Cortex: A TMS-EEG Study
S. Pillen, N. Knodel, C. Zrenner, U. Ziemann, T. Bergmann.
A setup for studying very early TMS-evoked EEG potentials: prospects and pitfalls
Daniel Schneider, Anna Göddertz, Henrike Haase, Clayton Hickey, Edmund Wascher.
Hemispheric asymmetries in EEG alpha oscillations indicate active inhibition during attentional orienting within working memory
Sofie Therese Hansen, Apit Hemakom, Mads Gylling Safeldt, Lærke Karen Krohne, Kristoffer Hougaard Madsen, Hartwig R. Siebner, Danilo P. Mandic, and Lars Kai Hansen.
Unmixing Oscillatory Brain Activity by EEG Source Localization and Empirical Mode Decomposition
Natalie Schaworonkow, Pedro Caldana Gordon, Paolo Belardinelli , Ulf Ziemann, Til Ole Bergmann and Christoph Zrenner.
μ-Rhythm Extracted With Personalized EEG Filters Correlates With Corticospinal Excitability in Real-Time Phase-Triggered EEG-TMS
Xiaheng Zhang.
Research on the Evaluation and Decision- Making of Product Premium Based on Electroencephalography (EEG) Testing Technology
Guangjun Wang, Shuyong Jia, Hongyan Li, Ze Wang & Weibo Zhang.
Exploring the Relationship between Blood Flux Signals and HRV following Different Thermal Stimulations using Complexity Analysis
R. E. Kallionpää, A. Scheinin, R. A. Kallionpää, N. Sandman, M. Kallioinen, R. Laitio, T. Laitio, K. Kaskinoro3, T. Kuusela, A. Revonsuo, H. Scheinin and K. Valli.
Spoken words are processed during dexmedetomidine-induced unresponsiveness
Daniel Schneider, Anna Barth, Henrike Haase, Clayton Hickey & Edmund Wascher.
Distractor inhibition contributes to retroactive attentional orienting within working memory: Evidence by lateralized event-related parameters of the EEG
L. Radek, R. E. Kallionpää, M. Karvonen, A. Scheinin, A. Maksimow, J. Långsjö, K. Kaisti, T. Vahlberg, A. Revonsuo, H. Scheinin and K. Valli.
Dreaming and awareness during dexmedetomidine and propofol-induced unresponsiveness
Annalotta Scheinin, M.D., Roosa E. Kallionpää, M.Sc., Duan Li, Ph.D., Minna Kallioinen, M.D., Kaike Kaisti, M.D., Jaakko Långsjö, M.D., Anu Maksimow, M.D., Tero Vahlberg, M.Sc., Katja Valli, Ph.D., George A. Mashour, M.D., Antti Revonsuo, Ph.D., Harry Scheinin, M.D..
Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram
Ivan Alekseichuk, Arnaud Y. Falchier, Gary Linn, Ting Xu, Michael P. Milham, Charles E. Schroeder, Alexander Opitz.
Electric Field Dynamics In The Brain During Multi-Electrode Transcranial Electric Stimulation
Martin Völker, Lukas D.J. Fiederer, Sofie Berberich, Jiří Hammer, Joos Behncke, Pavel Kršek, Martin Tomášek, Petr Marusič, Peter C. Reinacher, Volker A. Coenen, Moritz Helias, Andreas Schulze-Bonhage, Wolfram Burgard and Tonio Ball.
The Dynamics of Error Processing in the Human Brain as Reflected by High-Gamma Activity in Noninvasive and Intracranial EEG. Abbreviated title: High-Gamma Activity in Human Error Processing
D. Kuhner, L.D.J. Fiederer,, J. Aldinger, F. Burget, M. Völker, R.T. Schirrmeister, C. Do, J. Bödecker, B. Nebel, T. Ball, W. Burgard.
Deep Learning Based BCI Control of a Robotic Service Assistant Using Intelligent Goal Formulation
Nima Noury, Markus Siegel.
Analyzing EEG and MEG signals recorded during tES, a reply
Natalie Schaworonkow, Jochen Triesch, Ulf Ziemann, Christoph Zrenner.
EEG-triggered TMS reveals stronger brain state-dependent modulation of motor evoked potentials at weaker stimulation intensities
Christoph Zrenner , Debora Desideri , Paolo Belardinelli, Ulf Ziemann.
Real-time EEG-defined excitability states determine efficacy of TMS induced plasticity in human motor cortex
Juha Gogulski, Rasmus Zetter, Mikko Nyrhinen, Antti Pertovaara and Synnöve Carlson.
Neural Substrate for Metacognitive Accuracy of Tactile Working Memory
Martin Voelker, Sofie Berberich, Ecaterina Andreev, Lukas D.J. Fiederer, Wolfram Burgard, Tonio Ball.
BETWEEN-SUBJECT TRANSFER LEARNING FOR CLASSIFICATION OF ERROR-RELATED SIGNALS IN HIGH-DENSITY EEG
Nima Noury, Markus Siegel.
Phase properties of transcranial electrical stimulation artifacts in electrophysiological recordings
Mika Koivisto, Simone Grassini, Mikko Hurme, Niina Salminen-Vaparanta, HenryRailo, Victor Vorobyev, Jussi Tallu, Teemu Paavilainen, AnttiRevonsuo.
TMS-EEG reveals hemispheric asymmetries in top-down influences of posterior intraparietal cortex on behavior and visual event-related potentials
Leo Tomasevic, Mitsuaki Takemi, Hartwig Roman Siebner.
Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact
Edmund Wascher, Holger Heppner, Tina Möckel, Sven Oliver Kobald, Stephan Getzmann.
Eye-blinks in choice response tasks uncover hidden aspects of information processing
Dominik Welke, Joos Behncke, Marina Hader, Robin Tibor Schirrmeister, Andreas Schönau, Boris Eßmann, Oliver Müller, Wolfram Burgard, Tonio Ball.
Brain Responses During Robot-Error Observation
Martin Voelker, Lukas D. J. Fiederer, Sofie Berberich, Jiří Hammer, Joos Behncke, Pavel Kršek, Martin Tomášek, Petr Marusič, Peter C. Reinacher, Volker A. Coenen, Andreas Schulze-Bonhage, Wolfram Burgard, Tonio Ball.
Global and Local Dynamics of High-Gamma Activity Underlying Error Processing in the Human Brain Revealed by Noninvasive and Intracranial EEG
Robin Tibor Schirrmeister , Jost Tobias Springenberg, Lukas Dominique Josef Fiederer ,Martin Glasstetter, Katharina Eggensperger,Michael Tangermann, Frank Hutter, Wolfram Burgard, and Tonio Ball.
Deep Learning With Convolutional Neural Networks for EEG Decoding and Visualization
Felix Burget, Lukas Dominique Josef Fiederer, Daniel Kuhner, Martin Völker, Johannes Aldinger, Robin Tibor Schirrmeister, Chau Do, Joschka Boedecker, Bernhard Nebel, Tonio Ball, Wolfram Burgard.
Acting Thoughts: Towards a Mobile Robotic Service Assistant for Users with Limited Communication Skills
D. Desideri · P. Belardinelli · C. Zrenner · U. Ziemann.
Cortico-cortical excitability is influenced by the phase of oscillatory activity at the time of the stimulus
N. Schaworonkow, C. Zrenner, D. Desideri, U. Ziemann.
Influence of instantaneous phase on short-term plasticity induced by a single TMS burst
M.I. Stefanou · D. Desideri · P. Belardinelli.
Interhemispheric communication through neuronal coherence revealed by closed-loop EEG-dual-site-TMS
Syed Ariful Alam, Saara Pentikäinen, Johanna Närväinen, Ulla, Holopainen-Mantila, Kaisa Poutanen, Nesli Sozer.
Effects of structural and mechanical textural properties of brittle cereal foams on mechanisms of oral breakdown
Saara Pentikäinen, Nesli Sozer, Johanna Närväinen, Saara Ylätalo, Pekka Teppola, Jukka Jurvelin,Ulla Holopainen-Mantila, Riitta Törrönen, Anna-Marja Aura, Kaisa Poutanen.
Effects of wheat and rye bread structure on mastication process and bolus properties
Laura Sokka, Marianne Leinikka, Jussi Korpela, Andreas Henelius, Jani Lukander, Satu Pakarinen, Kimmo Alho, Minna Huotilainen.
Shifting of attentional set is inadequate in severe burnout: Evidence from an event-related potential study
Kimmo Alho, Laura Sokka, Marianne Leinikka, Jussi Korpela, Andreas Henelius, Lauri Ahonen,Claude Alain, Minna Huotilainen.
Job burnout is associated with dysfunctions in brain mechanisms of voluntary and involuntary attention
Noury, N., et al..
Physiological processes non-linearly affect electrophysiological recordings during transcranial electric stimulation
Christoph Zrenner, Paolo Belardinelli, Florian Müller-Dahlhaus and Ulf Ziemann.
Closed-Loop Neuroscience and Non-Invasive Brain Stimulation: A Tale of Two Loops
Guangjun Wang, Yuying Tian, Shuyong Jia, Wenting Zhou, Weibo Zhang.
Acupuncture Regulates the Heart Rate Variability
Wang Guangjun, Tian Yuying, Jia Shuyong, Zhou Wenting, and Zhang Weibo.
Bilateral Hegu Acupoints Have the Same Effect on the Heart Rate Variability of the Healthy Subjects
C. Zrenner, J. Tünnerhoff, C. Zipser, F. Müller-Dahlhaus, U. Ziemann.
Brain-state dependent non-invasive brain stimulation using closed-loop real-time EEG signal analysis to trigger a TMS pulse with millisecond accuracy
Laura Sokka, Minna Huotilainen, Marianne Leinikka, Jussi Korpela, Andreas Henelius , Claude Alain, Kiti Müller, Satu Pakarinen.
Alterations in attention capture to auditory emotional stimuli in job burnout: An event-related potential study
Satu Pakarinen, Laura Sokka, Marianne Leinikka, Andreas Henelius, Jussi Korpela,Minna Huotilainen.
Fast determination of MMN and P3a responses to linguistically and emotionally relevant changes in pseudoword stimuli
Henry Railo, Antti Revonsuo and Mika Koivisto.
Behavioral and electrophysiological evidence for fast emergence of visual consciousness
Christoph Zrenner, Johannes Tünnerhoff , Carl Zipser, Florian Müller-Dahlhaus.
Brain-state dependent brain stimulation: Real-time EEG alpha band analysis using sliding window FFT phase progression extrapolation to trigger an alpha phase locked TMS pulse with 1 millisecond accuracy
Kati Pettersson, Sharman Jagadeesan, Kristian Lukander, Andreas Henelius, Edward Hæggström and Kiti Müller.
Algorithm for automatic analysis of electro-oculographic data
Guangjun Wang, Yuying Tian, Shuyong Jia,Wenting Zhou, and Weibo Zhang.
Pilot Study of Acupuncture Point Laterality: Evidence from Heart Rate Variability
Nora Sihvola, Riitta Korpela, Andreas Henelius, Anu Holm, Minna Huotilainen, Kiti Müller, Tuija Poussa.
Breakfast high in whey protein or carbohydrates improves coping with workload in healthy subjects
Korpela, J. ; Brain Work Res. Centre, Finnish Inst. of Occupational Health, Helsinki, Finland ; Vigario, R. ; Huotilainen, M.
The effect of automatic blink correction on auditory evoked potentials
Korpela J, Huotilainen M..
Visual ERP P3 amplitude and latency in standalone and embedded visual processing task
Paavo Pitkänen, Jukka Kinnunen, Tarmo Lipping (IEEE, Senior Member).
A New Platform for Realtime BCI Applications.
Items marked with* are investigational devices and for research use only. CAUTION - Investigational Device. Limited by Federal (or United States) law to investigational use.
