Brain Ultimate TMS M-Series

A Yingchi Technology Innovation,
in Partnership with Brain Ultimate and Jali Medical

Brain Ultimate TMS M-Series by Yingchi Technology sets a new industry standard in Transcranial Magnetic Stimulation (TMS) with its superior precision, efficiency, and dependability, outperforming existing market offerings. It stands out as the first TMS system to achieve China's NMPA/CFDA Class III certification, further solidifying its leadership position through global recognitions such as FDA clearance, EU CE Marking, Australia's TGA, South Korea's KFDA and so on. This underscores its adherence to the highest international quality and safety standards.

Offering both air and liquid cooling technologies, Brain Ultimate TMS M-Series supports diverse application needs. Furthermore, its safety mechanism automatically shuts down when the coil temperature reaches 41°C, whereas the Quickstim software enhances data management and workflow efficiency, setting a new standard in TMS technology and research modalities.

Modular Configuration: Stimulator and cooling systems designed independently, enhancing safety by effectively separating liquid elements from electrical circuits.

All-in-One Software: Operate parameters easily without an external PC.

High-Frequency Stimulation: Up to 100Hz.

Theta-Burst Stimulation (TBS): Available without intensity decay.

Trigger In/Out Interface.

Cap with Pre-Defined Brain Regions: Positioned for precise targeting.

Built-In Coil Position Maps: Easily accessible within the software.

Flexible Coil Arm: Adaptability for optimal placement.

Singular Pulse Button: Enables efficient motor threshold measurement.

Intensity Control Buttons on the Coil: Facilitates fine-tuning for accuracy.

Thermal Regulation: Automatic shutdown triggered at 105.8°F (41℃) to prevent overheating.

Continuous Monitoring : Real-time tracking of liquid levels, temperature, and operational status.

Enhanced Data Security: Improved protection of subject data through dongle authorization.

Simplified File Management: Streamlines participant data handling, safeguarding study integrity.

Protocol Flexibility: Enables the creation of custom protocols or the use of evidence-based standards, ensuring thorough and innovative experimentation.

Comprehensive Session Logs: Detailed tracking of every experiment aids in analysis and reproducibility.

Efficient Reporting: One-click reports and data export, facilitating the documentation and publication process.

Cloud Connectivity: Facilitates remote access and collaboration, crucial for multicenter research.

Cooling Technology

The innovative liquid-cooling circulation system integrates an intelligent control module, liquid-cooled coil, specialized coolant, cooling-cycle unit, and robust power supply. This system utilizes a specialized liquid coolant known for its rapid temperature transmission, non-conductivity, excellent fluidity, and efficient cooling capabilities. With a compact oil pump and tank design, the system enables continuous fluid circulation between the coil and tank, ensuring minimal interference, consistent performance, reduced radiation, cost-effectiveness, and quiet operation.

Our coil, engineered for optimal performance, utilizes top-quality solid copper materials. It features an advanced oil cooling system that adeptly manages heat dissipation, ensuring the coil's continuous functionality.

Efficient Cooling: The patented technology guarantees seamless operation of the non-heating coil for 24 hours.

Durability: Resistant to electrolysis, corrosion, and blockages, ensuring long-lasting performance.

Low Maintenance: The in-house coolant rarely requires replacements or top-ups.

Safety: The closed external circulation system eliminates risks of liquid leakage, electric shock, or burns.

Smart Monitoring: Automated monitoring of temperature, circulatory volume, and circulatory state ensures device efficiency.

User-Friendly Coil Replacement: Effortlessly replace the coil when necessary.

Sham TMS

Enhanced Double-Blind Study Protocols

Brain Ultimate Sham TMS System is designed to mitigate the influence of the conventional "placebo effect" on result precision, offering an enhanced solution for placebo-controlled studies. By maintaining near-identical experimental operations and sensory effects between sham TMS and active TMS, our system facilitates genuinely randomized, double-blinded studies. This approach ensures the fulfillment of rigorous standards for result accuracy, reliability, and consistency in scientific research applications.

Intelligent Switching Between Active and Sham Modes: The Interface Module (IFM) is designed to control the connection between the stimulator and either an active or a sham coil. This is achieved by inserting a specialized smart card, the IFM Card, into the IFM. The card's embedded information directs the IFM to engage an electronic switch, which then connects the correct coil—active or sham—to the stimulator. This strategy ensures effective blinding of both the operator and the patient, maintaining the study's integrity.

Identical IFM Cards for Active and Sham Stimulations: The IFM cards, designed for either active or sham stimulation, are visually indistinguishable despite their differing built-in data content. The Principal Investigator/researcher entrust operator with the task of randomly distributing the stimulation cards with the goal of ensuring that neither the subjects nor the operators are aware of the card's type, facilitating a genuinely random allocation.

Single-blinded coil: This design eliminates the need for the IFM device. It features dual-sided functionality, with one side delivering active stimulation and the opposite side providing sham stimulation, thus blinding only the participant.

Double-blinded coil : This coil offers both active and sham stimulation capabilities on the same side, obviating the need to reposition or flip the coil. The auditory and vibratory outputs mimic those of actual stimulation, preserving the blinding of both the operator and the participant.

The placebo coils, available in circular and figure-8 configurations, incorporate advanced liquid cooling technology to enhance both the coil's longevity and participant safety.

Utilizing the IFM card reader, the IFM data analysis software enables the organization and analysis of stimulation data. This software complements the Brain Ultimate Transcranial Magnetic Stimulation (TMS) recording system, facilitating comprehensive data analysis and application in neurostimulation research.

Featured Researchers

MUSC's Neuro-X Lab

Neurocircuit strategy to decrease cocaine cue reactivity.
The new study explores the combined efficacy of continuous theta burst stimulation (cTBS) and N-acetylcysteine (NAC) as tools to restore corticostriatal circuitry function and dampen cue-induced craving in treatment-engaged individuals with cocaine use disorder.

Project Overview

The overarching goals of Project 4 are to evaluate the efficacy of combined cTBS + NAC on addiction pathophysiology in corticostriatal circuitry, and to bidirectionally translate our findings with preclinical results from Project 3. cTBS is a non-invasive brain stimulation tool that induces long-term depression (LTD) of neural excitability in the area stimulated and in monosynaptic targets. Recent data from our group demonstrates that a single dose of cTBS to the medial prefrontal cortex (mPFC) selectively decreases activity in the ventral striatum and subsequent craving.


MUSC Neuro-X Lab Team lead by Dr. Hesheng Liu, Dr. Bashar Badran, and Dr. Catherine Hubbard.

The video compilation presented by Yingchi Technology and listed on this page serves as an educational resource. It's crucial to acknowledge that this compilation does not make any claims to diagnose, treat, or cure any health conditions, adhering to US FDA guidelines. The purpose of this content is to highlight research findings utilizing this method in various fields, showcasing its potential shift from diagnostic practices to therapeutic interventions. Viewers should critically evaluate the material with an awareness of its limitations, except in cases where the application has been granted FDA clearance.

Effects of intermittent theta-burst transcranial magnetic stimulation on post-traumatic stress disorder symptoms: A randomized controlled trial

Psychiatry Research - 2023.1

The assessment of interhemispheric imbalance using functional near-infrared spectroscopic and transcranial magnetic stimulation for predicting motor outcome after stroke

Frontiers in Neuroscience - 2023.08

The VLPFC-Engaged Voluntary Emotion Regulation:Combined TMS-fMRI Evidence for the Neural Circuit of Cognitive Reappraisal

Journal of Neuroscience - 2023.08

Connectomic insight into unique stroke patient recovery after rTMS treatment

Frontiers in Neurology - 2023.07

The role of ventrolateral prefrontal cortex on voluntary emotion regulation of social pain

Human brain mapping - 2023.06

Effects on resting-state EEG phase-amplitude coupling in insomnia disorder patients following 1 Hz left dorsolateral prefrontal cortex rTMS

Human brain mapping - 2023.06

Motor cortical plasticity as a predictor of treatment response to high frequency repetitive transcranial magnetic stimulation (rTMS) for cognitive function in drug-naive patients with major depressive disorder

Journal of affective disorders - 2023.05

Efficacy of high-frequency repetitive transcranial magnetic stimulation in a family with spinocerebellar ataxia type 3: A case report

Heliyon - 2023.05

Case report: High-frequency repetitive transcranial magnetic stimulation for treatment of hereditary spastic paraplegia type 11

Frontiers in Neurology - 2023.05

Excitatory brain stimulation over the left dorsolateral prefrontal cortex enhances voluntary distraction in depressed patients

Psychological Medicine - 2023.02

The potential of electroencephalography coherence to predict the outcome of repetitive transcranial magnetic stimulation in insomnia disorder

Journal of psychiatric research - 2023.02

Theta-burst stimulation of TMS treatment for anxiety and depression: A fNIRS study

Journal of affective disorders - 2023.01

Default mode network mechanisms of repeated transcranial magnetic stimulation in heroin addiction

Brain imaging and behavior - 2022.11

The causal role of the bilateral ventrolateral prefrontal cortices on emotion regulation of social feedback

Human brain mapping - 2022.07

Repetitive transcranial magnetic stimulation modulates coupling among large-scale brain networks in heroin dependent individuals: A randomized resting-state functional magnetic resonance imaging study

Addiction biology - 2022.03

Effects of Acceptance and Commitment Therapy and Repetitive Transcranial Magnetic Stimulation on Obsessive–Compulsive Disorder

Frontiers in psychiatry - 2022.01

Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Thyroid Hormones Level and Cognition in the Recovery Stage of Stroke Patients with Cognitive Dysfunction

Medical science monitor : international medical journal of experimental and clinical research - 2021.10

Effect of transcranial magnetic stimulation on treatment effect and immune function

Saudi Journal of Biological Sciences - 2021.09

The VLPFC versus the DLPFC in Downregulating Social Pain Using Reappraisal and Distraction Strategies

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2021.02

The efficacy of repetitive transcranial magnetic stimulation on emotional processing in apathetic patients with Parkinson’s disease: A Placebo-controlled ERP study

Journal of affective disorders - 2020.12

Changes of resting-state EEG microstates induced by low-frequency repetitive transcranial magnetic stimulation

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. - 2020.07

The Lasting Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation on Resting State EEG in Healthy Subjects

IEEE Transactions On Neural Systems And Rehabilitation Engineering - 2020.04

The right VLPFC and downregulation of social pain: A TMS study

Human brain mapping - 2019.11

"High-Frequency Repetitive Transcranial Magnetic Stimulation Mediates Autophagy Flux in Human Bone Mesenchymal Stromal Cells via NMDA Receptor–Ca2+–Extracellular Signal-Regulated Kinase–Mammalian Target of Rapamycin Signaling"

Frontiers in neuroscience - 2019.11

The lasting effects of 1Hz repetitive transcranial magnetic stimulation on resting state EEG in healthy subjects

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. - 2019.07


Items marked with* are investigational devices and for research use only. CAUTION - Investigational Device. Limited by Federal (or United States) law to investigational use.